Increased Elongase 6 and Δ9-Desaturase Activity are Associated with n-7 and n-9 Fatty Acid Changes in Cystic Fibrosis
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چکیده
منابع مشابه
Overall and Abdominal Obesity Are Inversely Associated With Plasma n-3 Polyunsaturated Fatty Acids in Iranian Adults
Background: Obesity is a common health problem associated with a number of diseases, such as hypertension, cardiovascular disease, hyperlipidemia, diabetes, gout, gall bladder and liver disease, cancer, and depression. The prevalence of obesity is dramatically increasing around the world, especially in the Asia Pacific region. omega-3 is a type of polyunsaturated fatty acids that have several ...
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5 and 6 fatty acid desaturases are critical enzymes in the pathways for the biosynthesis of the polyunsaturated fatty acids arachidonic, eicosapentaenoic, and docosahexaenoic acids. They are encoded by distinct genes in mammals and Caenorhabditis elegans. This paper describes a cDNA isolated from zebrafish (Danio rerio) with high similarity to mammalian 6 desaturase genes. The 1,590-bp sequence...
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the aim followed in this study was to investigate the effects of soybean oil (high in c18:2 n-6, an omega-6 fatty acid) and fish oil (high in epa 20:5 n-3 and dha 22:6 n-3, omega-3 fatty acids) on meat quality and on the fatty acid profiles in goat kids. twenty-four male kids were allocated through stratified randomization and on the basis of body weight (19.43±1.2 kg) into three equal groups. ...
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Bioactive food components containing n-3 polyunsaturated fatty acids (PUFA) modulate multiple determinants that link inflammation to cancer initiation and progression. Therefore, in this study, fat-1 transgenic mice, which convert endogenous n-6 PUFA to n-3 PUFA in multiple tissues, were injected with azoxymethane followed by three cycles of dextran sodium sulfate (DSS) to induce colitis-associ...
متن کاملRegulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity.
Fatty acid elongases and desaturases play an important role in hepatic and whole body lipid composition. We examined the role that key transcription factors played in the control of hepatic elongase and desaturase expression. Studies with peroxisome proliferator-activated receptor alpha (PPARalpha)-deficient mice establish that PPARalpha was required for WY14643-mediated induction of fatty acid...
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ژورنال
عنوان ژورنال: Lipids
سال: 2011
ISSN: 0024-4201,1558-9307
DOI: 10.1007/s11745-011-3563-z